Dr Gaynor Miller, BSc (Hons), PhD, PGCertHE, FHEA
Lecturer Academic Unit of Bone Biology
Tel: +44 (0) 114 271 2112
Secretary, Gillian Griffiths, Tel: +44 (0)114 2713518
Dr Miller graduated from the University of Sheffield in 1992 with a BSc in Genetics. After a brief period working in the research laboratories at the Forensic Science Service she began her PhD at the University of London on ‘Modelling Gene Therapy for Haemophilia’ where her interest in muscle began. Dr Miller did her first post doctoral position at the University of Leeds looking at mutations in the beta cardiac myosin heavy chain gene associated with familial hypertrophic cardiomyopathy. Dr Miller then spent the next five years at the University of California Los Angeles, first as a Post-doctoral Research Fellow then when she got her own funding as an Assistant Researcher. It was during this time that her research into the molecular basis of muscle wasting began. She returned to the University of Sheffield in 2006 to take up her current position as Lecturer.
Dr Miller’s main research interests are unravelling the molecular and cellular basis of muscle wasting and determining the role of macrophages in disease. Current projects in her laboratory include: determining the role of macrophages on tumour progression (with Prof Gill Tozer); combating macrophage induced muscle damage (with Dr Neil Chapman, Dr Allie Gartland and Prof Steve Winder); investigating the role of CD68+ve cells and NF-kB in muscular dystrophy (with Dr Neil Chapman) and determining the potential of tryosine phosphorylation as a target for muscular dystrophy treatment (with Prof Steve Winder). Dr Miller’s group employ a wide variety of in vitro and in vivo techniques to tackle these projects.