Professor Paul Dimitri BSc, MBChB, FRCPCH, PhD
Director of Research and Innovation at Sheffield Children’s Hospital Consultant Paediatric Endocrinologist and Honorary Senior Clinical Lecturer, Deputy Director for the Medicines for Children Research Network (East)
The relationship between fat and bone in children and novel methods of bone imaging
Paul studied Medicine at the University of St Andrew’s where he received a medal in pathology and the University of Manchester where he received a distinction in Paediatrics. He moved to Sheffield in 1998 where he trained in Paediatrics and Paediatric Endocrinology. In 2010 he was awarded a PhD in Medicine for his work on the relationship of fat and bone in children, and received his Fellowship for the Royal College of Paediatrics and Child Health. Paul currently works as a Consultant in Paediatric Endocrinology at Sheffield Children’s Hospital. He was appointed the Director of Research and Innovation and the Deputy Director for the Medicines for Children Research Network (East) in 2012.
Paul’s research interests include the relationship between fat and bone in children and the development of novel imaging method of bone in children and adults. He is currently working on projects studying the effect of obesity on skeletal growth, the effects of monogenic obesity syndromes on bone density, architecture and strength and development from childhood to early adulthood, and the development of High Resolution peripheral Quantitative Computed Tomography (HRpQCT) and Magnetic Resonance Imaging (MRI) for skeletal and bone marrow analysis in children and young adults. Paul’s work on the relationships between fat and bone in skeletal development focuses on the impact of obesity on bone mass, structure and strength during skeletal development, and the relationships between adipokines and markers of bone turnover. His work on MRI imaging of bone is based upon developing an accurate radiation free method of cortical and trabecular bone imaging and bone marrow analysis which is applicable to clinical diagnostics and the longitudinal study of skeletal growth and development in children.